Bold indicates ones that have been read.
Italics indicate ones that may be read.
Dave Langford's Top 20 sf novels ever, up to 1990
20) Terry Pratchett, Guards! Guards! (1989)
19) Frederik Pohl: Gateway (1977)
18) Iain M. Banks, Consider Phlebas (1987)
17) C.J. Cherryh, Cyteen (1988)
16) Barry Hughart: Bridge of Birds (1984)
15) Christopher Priest, The Affirmation (1981)
14) Roger Zelazny, Lord of Light (1967)
13) Philip K. Dick, The Three Stigmata of Palmer Eldritch (1965)
12) Alan Garner, The Owl Service (1967)
11) Alfred Bester, The Stars My Destination (1956, alias Tiger! Tiger!)
10) Algis Budrys: Rogue Moon (1960)
9) Greg Bear, Blood Music (1985)
8) Frank Herbert: Dune (1965)
7) Mervyn Peake: Gormenghast (1946-59)
It lives in the "never really started" pile...
6) Ursula Le Guin: Earthsea (1968-72)
5) Keith Roberts, Pavane (1968)
4) J.R.R. Tolkien: The Lord of the Rings (1954-55)
3) Arthur C. Clarke: The City and the Stars (1956)
2) John Crowley: Little, Big (1981)
1) Gene Wolfe: The Book of the New Sun (1980-83)
It's striking that, whilst I've read a good few (7/20), I have very little feeling about the ones I've not read. I neither have a strong urge to read them, nor a strong urge not to.
I have always said I'm not that big a fan of SF.